KMID : 0387820100170010059
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Clinical Pediatric Hematology-Oncology 2010 Volume.17 No. 1 p.59 ~ p.63
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A Case of Concurrent Cholestatic Jaundice and Hemolytic Anemia Due to Epstein-Barr Virus Infection
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Hong Yeon-Ju
Choi Hye-Sun Hwang Hui-Sung Lee Soo-Young Chung Seung-Yun Kang Jin-Han Jeong Chang-Mo
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Abstract
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The patients infected with Epstein-Barr virus (EBV) experienced asymptomatic or mild flu-like illness. Most of symptoms with EBV infection were disappeared within several weeks, although there were various clinical manifestations. Jaundice with elevated liver enzymes was shown about 5~25%, but hemolytic anemia was rare during EBV infection. Some cases due to EBV infection had been persistent or aggravated course of hemolytic anemia. A twelve-year-old boy was admitted due to fever, and jaundice. Total bilirubin with direct bilirubin was elevated with moderately increased aminotransferase levels. He developed mild hemolytic anemia with positive Coomb¡¯s test and high titer of cold agglutinin during hospitalization. The symptoms were spontaneously improved with conservative care. We report a case of concurrent cholestatic jaundice with hemolytic anemia during acute EBV infection.
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KEYWORD
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Epstein-Barr virus, Cholestatic jaundice, Hemolytic anemia
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